Companies: 10,852     total market cap: $146.706 T
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SPDR S&P Biotech ETF
XBI
#351
ETF rank
$7.83 B
Marketcap
🇺🇸 US
Market
$128.67
Share price
-3.56%
Change (1 day)
55.91%
Change (1 year)
🧬 Biotech ETFs
Categories

SPDR S&P Biotech ETF - Holdings

Etf holdings as of June 4, 2026Number of holdings: 153

Full holdings list

Weight %NameTickerShares Held
1.82%
TWIST BIOSCIENCE CORPTWST2005403.000
1.80%
REVOLUTION MEDICINES INCRVMD943456.000
1.80%
ALKERMES PLCALKS3383778.000
1.80%
TRAVERE THERAPEUTICS INCTVTX3175662.000
1.67%
TG THERAPEUTICS INCTGTX3349851.000
1.49%
ARROWHEAD PHARMACEUTICALS INARWR1617337.000
1.49%
NEUROCRINE BIOSCIENCES INCNBIX725345.000
1.45%
BEAM THERAPEUTICS INCBEAM3603394.000
1.45%
EXELIXIS INCEXEL2250752.000
1.40%
APOGEE THERAPEUTICS INCAPGE1258310.000
1.39%
KRYSTAL BIOTECH INCKRYS368523.000
1.33%
VERACYTE INCVCYT2171414.000
1.32%
MADRIGAL PHARMACEUTICALS INCMDGL217786.000
1.31%
CRISPR THERAPEUTICS AGCRSP1882200.000
1.31%
CYTOKINETICS INCCYTK1476804.000
1.30%
NATERA INCNTRA477920.000
1.24%
HALOZYME THERAPEUTICS INCHALO1413632.000
1.24%
PTC THERAPEUTICS INCPTCT1430991.000
1.23%
INCYTE CORPINCY992868.000
1.23%
PROTAGONIST THERAPEUTICS INCPTGX974094.000
1.21%
SCHOLAR ROCK HOLDING CORPSRRK2176330.000
1.19%
BIOGEN INCBIIB493338.000
1.16%
MIRUM PHARMACEUTICALS INCMIRM1024160.000
1.16%
UNITED THERAPEUTICS CORPUTHR172521.000
1.16%
IONIS PHARMACEUTICALS INCIONS1256554.000
1.15%
ROIVANT SCIENCES LTDROIV3177067.000
1.14%
SPYRE THERAPEUTICS INCSYRE1186023.000
1.14%
IMMUNOVANT INCIMVT2846711.000
1.14%
ABBVIE INCABBV412768.000
1.12%
RHYTHM PHARMACEUTICALS INCRYTM1043992.000
1.09%
ALNYLAM PHARMACEUTICALS INCALNY293269.000
1.09%
BRIDGEBIO PHARMA INCBBIO1316427.000
1.08%
NUVALENT INC ANUVL939333.000
1.08%
BIOMARIN PHARMACEUTICAL INCBMRN1558036.000
1.06%
MODERNA INCMRNA1679197.000
1.05%
AMGEN INCAMGN248871.000
1.05%
KYMERA THERAPEUTICS INCKYMR1152737.000
1.05%
COGENT BIOSCIENCES INCCOGT2604754.000
1.03%
VERTEX PHARMACEUTICALS INCVRTX190881.000
1.03%
PRAXIS PRECISION MEDICINES IPRAX316462.000
1.03%
ARCUTIS BIOTHERAPEUTICS INCARQT3813732.000
1.02%
GILEAD SCIENCES INCGILD643735.000
1.02%
IMMUNITYBIO INCIBRX1.136372E7
1.01%
ACADIA PHARMACEUTICALS INCACAD3785449.000
0.99%
ULTRAGENYX PHARMACEUTICAL INRARE3446949.000
0.98%
SUMMIT THERAPEUTICS INCSMMT5397775.000
0.98%
DISC MEDICINE INCIRON1122506.000
0.98%
VAXCYTE INCPCVX1633534.000
0.97%
CG ONCOLOGY INCCGON1416363.000
0.97%
CATALYST PHARMACEUTICALS INCCPRX2515722.000
0.96%
VIKING THERAPEUTICS INCVKTX2628159.000
0.94%
GRAIL INCGRAL1154861.000
0.94%
REGENERON PHARMACEUTICALSREGN121338.000
0.92%
CELCUITY INCCELC811751.000
0.87%
VERA THERAPEUTICS INCVERA2120831.000
0.87%
INSMED INCINSM674187.000
0.86%
RECURSION PHARMACEUTICALS ARXRX1.8561448E7
0.86%
DYNE THERAPEUTICS INCDYN3812912.000
0.85%
ERASCA INCERAS5251497.000
0.79%
IMMUNOME INCIMNM3255315.000
0.78%
DENALI THERAPEUTICS INCDNLI3140503.000
0.77%
BIOCRYST PHARMACEUTICALS INCBCRX7382351.000
0.76%
AGIOS PHARMACEUTICALS INCAGIO2141180.000
0.75%
INTELLIA THERAPEUTICS INCNTLA4163330.000
0.73%
ARCUS BIOSCIENCES INCRCUS2399443.000
0.69%
SAREPTA THERAPEUTICS INCSRPT3390697.000
0.67%
DIANTHUS THERAPEUTICS INCDNTH650744.000
0.65%
IDEAYA BIOSCIENCES INCIDYA1806735.000
0.65%
NOVAVAX INCNVAX5177984.000
0.65%
UNIQURE NVQURE1881606.000
0.64%
ORUKA THERAPEUTICS INCORKA843768.000
0.62%
KODIAK SCIENCES INCKOD1490299.000
0.60%
MINERALYS THERAPEUTICS INCMLYS1966716.000
0.60%
VIRIDIAN THERAPEUTICS INCVRDN2959201.000
0.60%
BIOHAVEN LTDBHVN4264562.000
0.59%
TANGO THERAPEUTICS INCTNGX2187641.000
0.58%
NURIX THERAPEUTICS INCNRIX3116539.000
0.58%
SELLAS LIFE SCIENCES GROUP ISLS5200239.000
0.57%
SYNDAX PHARMACEUTICALS INCSNDX2599555.000
0.56%
ARDELYX INCARDX8500622.000
0.56%
RELAY THERAPEUTICS INCRLAY3140085.000
0.54%
VERICEL CORPVCEL1238249.000
0.53%
ADMA BIOLOGICS INCADMA5455043.000
0.52%
MANNKIND CORPMNKD1.2124086E7
0.50%
CELLDEX THERAPEUTICS INCCLDX1356017.000
0.48%
IOVANCE BIOTHERAPEUTICS INCIOVA9029528.000
0.47%
CAREDX INCCDNA1641836.000
0.46%
MONTE ROSA THERAPEUTICS INCGLUE2181041.000
0.46%
STOKE THERAPEUTICS INCSTOK1248833.000
0.45%
ABSCI CORPABSI5025799.000
0.45%
TAYSHA GENE THERAPIES INCTSHA6252408.000
0.45%
CAPRICOR THERAPEUTICS INCCAPR1299968.000
0.43%
PALVELLA THERAPEUTICS INCPVLA304162.000
0.39%
KALVISTA PHARMACEUTICALS INCKALV1194867.000
0.37%
INHIBRX BIOSCIENCES INCINBX328667.000
0.36%
ANAPTYSBIO INCANAB568115.000
0.36%
OLEMA PHARMACEUTICALS INCOLMA2742060.000
0.34%
CORVUS PHARMACEUTICALS INCCRVS2348306.000
0.32%
HYPERLIQUID STRATEGIESPURR2735876.000
0.32%
PRECIGEN INCPGEN6657234.000
0.31%
VIR BIOTECHNOLOGY INCVIR2803876.000
0.31%
ARRIVENT BIOPHARMA INCAVBP767606.000
0.30%
KURA ONCOLOGY INCKURA2798289.000
0.30%
REPLIMUNE GROUP INCREPL2441001.000
0.29%
RIGEL PHARMACEUTICALS INCRIGL785909.000
0.28%
ANNEXON INCANNX4241104.000
0.27%
GERON CORPGERN1.8431763E7
0.27%
ARS PHARMACEUTICALS INCSPRY2423538.000
0.27%
SANA BIOTECHNOLOGY INCSANA7377229.000
0.26%
JANUX THERAPEUTICS INCJANX1560366.000
0.26%
CULLINAN THERAPEUTICS INCCGEM1449705.000
0.25%
SAVARA INCSVRA3893110.000
0.24%
TYRA BIOSCIENCES INCTYRA727016.000
0.23%
ORIC PHARMACEUTICALS INCORIC2379340.000
0.23%
XENCOR INCXNCR1557230.000
0.22%
ZENAS BIOPHARMA INCZBIO992530.000
0.21%
SIONNA THERAPEUTICS INCSION456126.000
0.20%
BICARA THERAPEUTICS INCBCAX782941.000
0.19%
CYTOMX THERAPEUTICS INCCTMX4941169.000
0.19%
PRIME MEDICINE INCPRME4441793.000
0.19%
IRONWOOD PHARMACEUTICALS INCIRWD4463130.000
0.18%
VOR BIOPHARMA INCVOR1040623.000
0.18%
EMERGENT BIOSOLUTIONS INCEBS1755370.000
0.18%
4D MOLECULAR THERAPEUTICS INFDMT1471049.000
0.17%
ALTIMMUNE INCALT4764997.000
0.15%
VANDA PHARMACEUTICALS INCVNDA1901821.000
0.15%
ALLOGENE THERAPEUTICS INCALLO5817405.000
0.14%
MYRIAD GENETICS INCMYGN2410940.000
0.14%
ARBUTUS BIOPHARMA CORPABUS2531168.000
0.13%
REGENXBIO INCRGNX1522157.000
0.13%
FIRST TRACKS BIOTHERAPEUTICSTRAX561315.000
0.12%
PROTHENA CORP PLCPRTA1097518.000
0.12%
LEXEO THERAPEUTICS INCLXEO2078869.000
0.12%
MIMEDX GROUP INCMDXG2547629.000
0.11%
VERASTEM INCVSTM2248264.000
0.11%
COMPASS THERAPEUTICS INCCMPX4035510.000
0.10%
ROCKET PHARMACEUTICALS INCRCKT2909473.000
0.10%
ANAVEX LIFE SCIENCES CORPAVXL2961789.000
0.10%
OCUGEN INCOCGN5828867.000
0.09%
CONTRA METSERA INC-1530714.000
0.09%
INVIVYD INCIVVD6310696.000
0.08%
AKEBIA THERAPEUTICS INCAKBA6739633.000
0.08%
PERSPECTIVE THERAPEUTICS INCCATX1912295.000
0.04%
SSI US GOV MONEY MARKET CLASS-3108636.860
0.03%
DAMORA THERAPEUTICS INCDMRA104656.000
0.02%
CONTRA AKERO THERAPEUT-2033975.000
0.01%
CONTRA INHIBRX INC-1645973.000
0.01%
CONTRA MIRATI THERAPEU-1369552.000
0.01%
US DOLLAR-630309.410
0.01%
CONTRA VERVE THERAPEUT-900273.000
0.00%
CONTRA BLUEPRINT MEDIC-756469.000
0.00%
OMNIAB INC 12.5 EARNOUT2200963D161959.000
0.00%
OMNIAB INC 15.00 EARNOUT2200964D161959.000

What is the market capitalization of a company?

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In most cases it can be easily calculated by multiplying the share price with the amount of outstanding shares.

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