As of December 2025 Spyre Therapeutics has a market cap of โน242.21 Billion. This makes Spyre Therapeutics the world's 4128th most valuable company by market cap according to our data. The market capitalization, commonly called market cap, is the total market value of a publicly traded company's outstanding shares and is commonly used to measure how much a company is worth.
On Dec 8th, 2025 the market cap of Spyre Therapeutics was reported to be: