As of February 2026 Spyre Therapeutics has a market cap of โน224.68 Billion. This makes Spyre Therapeutics the world's 4359th most valuable company by market cap according to our data. The market capitalization, commonly called market cap, is the total market value of a publicly traded company's outstanding shares and is commonly used to measure how much a company is worth.
On Feb 4th, 2026 the market cap of Spyre Therapeutics was reported to be: