Companies: 10,793     total market cap: C$187.207 T
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SPDR S&P Biotech ETF
XBI
#334
ETF rank
C$10.47 B
Marketcap
🇺🇸 US
Market
C$179.85
Share price
0.32%
Change (1 day)
61.68%
Change (1 year)
🧬 Biotech ETFs
Categories

SPDR S&P Biotech ETF - Holdings

Etf holdings as of April 1, 2026Number of holdings: 157

Full holdings list

Weight %NameTickerShares Held
1.83%
APELLIS PHARMACEUTICALS INCAPLS3835144.000
1.43%
ALKERMES PLCALKS3450990.000
1.39%
MADRIGAL PHARMACEUTICALS INCMDGL222028.000
1.36%
TG THERAPEUTICS INCTGTX3416496.000
1.34%
INSMED INCINSM687450.000
1.29%
SCHOLAR ROCK HOLDING CORPSRRK2219385.000
1.28%
APOGEE THERAPEUTICS INCAPGE1283234.000
1.23%
SUMMIT THERAPEUTICS INCSMMT5504813.000
1.23%
ARROWHEAD PHARMACEUTICALS INARWR1649442.000
1.22%
PRAXIS PRECISION MEDICINES IPRAX322767.000
1.22%
PROTAGONIST THERAPEUTICS INCPTGX993361.000
1.20%
TRAVERE THERAPEUTICS INCTVTX3238755.000
1.20%
TWIST BIOSCIENCE CORPTWST2045326.000
1.20%
NUVALENT INC ANUVL957788.000
1.19%
EXELIXIS INCEXEL2295480.000
1.19%
UNITED THERAPEUTICS CORPUTHR175965.000
1.19%
PTC THERAPEUTICS INCPTCT1459346.000
1.19%
CYTOKINETICS INCCYTK1506218.000
1.18%
BRIDGEBIO PHARMA INCBBIO1342366.000
1.18%
KYMERA THERAPEUTICS INCKYMR1175615.000
1.17%
NATERA INCNTRA487358.000
1.17%
MIRUM PHARMACEUTICALS INCMIRM1044558.000
1.16%
ALNYLAM PHARMACEUTICALS INCALNY299176.000
1.16%
NEUROCRINE BIOSCIENCES INCNBIX739749.000
1.15%
VAXCYTE INCPCVX1665780.000
1.15%
KRYSTAL BIOTECH INCKRYS375892.000
1.14%
CG ONCOLOGY INCCGON1444365.000
1.14%
AMICUS THERAPEUTICS INCFOLD6669150.000
1.14%
IONIS PHARMACEUTICALS INCIONS1281441.000
1.14%
REGENERON PHARMACEUTICALSREGN123735.000
1.14%
ARCELLX INCACLX838080.000
1.13%
INCYTE CORPINCY1012438.000
1.12%
REVOLUTION MEDICINES INCRVMD962398.000
1.11%
HALOZYME THERAPEUTICS INCHALO1441629.000
1.11%
RHYTHM PHARMACEUTICALS INCRYTM1064687.000
1.11%
ARCUTIS BIOTHERAPEUTICS INCARQT3888900.000
1.11%
CRISPR THERAPEUTICS AGCRSP1919451.000
1.11%
COGENT BIOSCIENCES INCCOGT2656151.000
1.10%
CELCUITY INCCELC828000.000
1.09%
BIOGEN INCBIIB503110.000
1.09%
GILEAD SCIENCES INCGILD656514.000
1.07%
BIOMARIN PHARMACEUTICAL INCBMRN1588821.000
1.07%
ABBVIE INCABBV420903.000
1.07%
ROIVANT SCIENCES LTDROIV3239997.000
1.06%
AMGEN INCAMGN253934.000
1.05%
BEAM THERAPEUTICS INCBEAM3674711.000
1.05%
ERASCA INCERAS5353877.000
1.04%
VIKING THERAPEUTICS INCVKTX2679984.000
1.03%
VERA THERAPEUTICS INCVERA2162764.000
1.03%
VERTEX PHARMACEUTICALS INCVRTX194648.000
1.02%
ACADIA PHARMACEUTICALS INCACAD3860395.000
1.01%
MODERNA INCMRNA1712275.000
0.98%
IMMUNITYBIO INCIBRX1.1587963E7
0.90%
SAREPTA THERAPEUTICS INCSRPT3457908.000
0.89%
ULTRAGENYX PHARMACEUTICAL INRARE3515425.000
0.88%
AGIOS PHARMACEUTICALS INCAGIO2183474.000
0.88%
IMMUNOME INCIMNM3319712.000
0.88%
DISC MEDICINE INCIRON1144723.000
0.86%
IMMUNOVANT INCIMVT2903248.000
0.85%
VERACYTE INCVCYT2214491.000
0.83%
BIOCRYST PHARMACEUTICALS INCBCRX7527964.000
0.83%
DYNE THERAPEUTICS INCDYN3888314.000
0.77%
KODIAK SCIENCES INCKOD1520441.000
0.75%
CATALYST PHARMACEUTICALS INCCPRX2565667.000
0.75%
SYNDAX PHARMACEUTICALS INCSNDX2650631.000
0.75%
GRAIL INCGRAL1177935.000
0.74%
DENALI THERAPEUTICS INCDNLI3202039.000
0.74%
SOLENO THERAPEUTICS INCSLNO1692193.000
0.71%
IDEAYA BIOSCIENCES INCIDYA1842226.000
0.70%
SPYRE THERAPEUTICS INCSYRE1209856.000
0.68%
RECURSION PHARMACEUTICALS ARXRX1.8927094E7
0.68%
VIRIDIAN THERAPEUTICS INCVRDN3016842.000
0.67%
INTELLIA THERAPEUTICS INCNTLA4245603.000
0.66%
DIANTHUS THERAPEUTICS INCDNTH663533.000
0.63%
ARCUS BIOSCIENCES INCRCUS2447013.000
0.63%
ARDELYX INCARDX8669423.000
0.63%
MINERALYS THERAPEUTICS INCMLYS2005658.000
0.60%
ADMA BIOLOGICS INCADMA5560862.000
0.58%
NURIX THERAPEUTICS INCNRIX3178317.000
0.56%
TANGO THERAPEUTICS INCTNGX2231211.000
0.51%
ORUKA THERAPEUTICS INCORKA860768.000
0.51%
CELLDEX THERAPEUTICS INCCLDX1382910.000
0.50%
NOVAVAX INCNVAX5279850.000
0.50%
OLEMA PHARMACEUTICALS INCOLMA2795897.000
0.49%
BIOHAVEN LTDBHVN4348650.000
0.49%
VERICEL CORPVCEL1262652.000
0.48%
STOKE THERAPEUTICS INCSTOK1273292.000
0.47%
CAPRICOR THERAPEUTICS INCCAPR1325614.000
0.45%
MONTE ROSA THERAPEUTICS INCGLUE2224456.000
0.44%
PALVELLA THERAPEUTICS INCPVLA310222.000
0.41%
CORVUS PHARMACEUTICALS INCCRVS2394408.000
0.41%
RELAY THERAPEUTICS INCRLAY3202824.000
0.39%
ANAPTYSBIO INCANAB579275.000
0.38%
UNIQURE NVQURE1919747.000
0.38%
IOVANCE BIOTHERAPEUTICS INCIOVA9206763.000
0.37%
MANNKIND CORPMNKD1.2366655E7
0.37%
GERON CORPGERN1.8790891E7
0.35%
CAREDX INCCDNA1674399.000
0.34%
TYRA BIOSCIENCES INCTYRA741467.000
0.32%
TAYSHA GENE THERAPIES INCTSHA6377926.000
0.32%
DAY ONE BIOPHARMACEUTICALS IDAWN1259191.000
0.32%
PRECIGEN INCPGEN6791389.000
0.30%
VIR BIOTECHNOLOGY INCVIR2859025.000
0.28%
KALVISTA PHARMACEUTICALS INCKALV1219167.000
0.28%
KURA ONCOLOGY INCKURA2853850.000
0.28%
JANUX THERAPEUTICS INCJANX1611200.000
0.27%
CYTOMX THERAPEUTICS INCCTMX5101929.000
0.27%
ANNEXON INCANNX4324178.000
0.27%
SANA BIOTECHNOLOGY INCSANA7521663.000
0.27%
COMPASS THERAPEUTICS INCCMPX4167607.000
0.27%
INHIBRX BIOSCIENCES INCINBX335316.000
0.27%
SAVARA INCSVRA4020508.000
0.26%
SELLAS LIFE SCIENCES GROUP ISLS5304385.000
0.26%
RIGEL PHARMACEUTICALS INCRIGL801496.000
0.25%
ZENAS BIOPHARMA INCZBIO1024900.000
0.24%
CULLINAN THERAPEUTICS INCCGEM1478566.000
0.24%
ARS PHARMACEUTICALS INCSPRY2503256.000
0.24%
XENCOR INCXNCR1608518.000
0.23%
SIONNA THERAPEUTICS INCSION471225.000
0.23%
ARRIVENT BIOPHARMA INCAVBP792893.000
0.22%
REPLIMUNE GROUP INCREPL2490271.000
0.22%
VOR BIOPHARMA INCVOR1056840.000
0.22%
ORIC PHARMACEUTICALS INCORIC2456077.000
0.21%
IRONWOOD PHARMACEUTICALS INCIRWD4532974.000
0.19%
BICARA THERAPEUTICS INCBCAX795278.000
0.19%
ABSCI CORPABSI5042288.000
0.18%
ALTIMMUNE INCALT4922939.000
0.18%
PRIME MEDICINE INCPRME4511303.000
0.18%
ALLOGENE THERAPEUTICS INCALLO5908311.000
0.18%
EMERGENT BIOSOLUTIONS INCEBS1782765.000
0.17%
4D MOLECULAR THERAPEUTICS INFDMT1494053.000
0.17%
HYPERLIQUID STRATEGIESPURR2778601.000
0.16%
VANDA PHARMACEUTICALS INCVNDA1931561.000
0.16%
REGENXBIO INCRGNX1545895.000
0.15%
VERASTEM INCVSTM2283509.000
0.14%
LEXEO THERAPEUTICS INCLXEO2111282.000
0.14%
ARBUTUS BIOPHARMA CORPABUS2570733.000
0.13%
MYRIAD GENETICS INCMYGN2448546.000
0.13%
PROTHENA CORP PLCPRTA1114598.000
0.13%
ROCKET PHARMACEUTICALS INCRCKT2954987.000
0.13%
OCUGEN INCOCGN5919852.000
0.12%
MIMEDX GROUP INCMDXG2587355.000
0.11%
AKEBIA THERAPEUTICS INCAKBA6845112.000
0.11%
ANAVEX LIFE SCIENCES CORPAVXL3007988.000
0.10%
PERSPECTIVE THERAPEUTICS INCCATX1942245.000
0.10%
INVIVYD INCIVVD6409303.000
0.09%
CONTRA METSERA INC-1530714.000
0.06%
SSI US GOV MONEY MARKET CLASS-4727648.670
0.03%
DAMORA THERAPEUTICS INCDMRA106302.000
0.02%
CONTRA AKERO THERAPEUT-2033975.000
0.01%
CONTRA INHIBRX INC-1645973.000
0.01%
CONTRA MIRATI THERAPEU-1369552.000
0.01%
CONTRA VERVE THERAPEUT-900273.000
0.00%
CONTRA BLUEPRINT MEDIC-756469.000
0.00%
US DOLLAR-24231.000
0.00%
OMNIAB INC 12.5 EARNOUT2200963D161959.000
0.00%
OMNIAB INC 15.00 EARNOUT2200964D161959.000

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