As of December 2025 Spyre Therapeutics has a market cap of A$4.05 Billion. This makes Spyre Therapeutics the world's 4128th most valuable company by market cap according to our data. The market capitalization, commonly called market cap, is the total market value of a publicly traded company's outstanding shares and is commonly used to measure how much a company is worth.
On Dec 8th, 2025 the market cap of Spyre Therapeutics was reported to be: