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total market cap:
NZ$234.502 T
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Watchlist
Account
ALPS Medical Breakthroughs ETF
SBIO
#2252
ETF rank
NZ$0.18 B
Marketcap
๐บ๐ธ US
Market
NZ$87.33
Share price
0.60%
Change (1 day)
40.66%
Change (1 year)
๐ก Innovation ETFs
๐งฌ Biotech ETFs
Categories
Market cap
Price history
Shares outstanding
Cost to borrow
Premium/Discount
Fees (Expense ratio)
Holdings
More
Cost to borrow
Premium/Discount
Fees (Expense ratio)
Distributions
ALPS Medical Breakthroughs ETF - Holdings
Etf holdings as of
December 5, 2025
Number of holdings:
102
Full holdings list
Weight %
Name
Ticker
ISIN
Shares Held
4.42%
Avidity Biosciences Inc.
RNA
US05370A1088
69096
3.50%
Arrowhead Pharmaceuticals Inc.
ARWR
US04280A1007
63821
3.25%
Cytokinetics Inc.
CYTK
US23282W6057
55437
3.19%
Axsome Therapeutics Inc.
AXSM
US05464T1043
23936
3.01%
Rhythm Pharmaceuticals Inc.
RYTM
US76243J1051
32292
2.96%
Merus NV
MRUS
NL0011606264
34557
2.95%
Nuvalent Inc.
NUVL
US6707031075
30195
2.74%
Krystal Biotech Inc.
KRYS
US5011471027
13101
2.49%
PTC Therapeutics Inc.
PTCT
US69366J2006
36139
2.47%
Vaxcyte Inc.
PCVX
US92243G1085
59625
2.29%
Protagonist Therapeutics Inc.
PTGX
US74366E1029
28609
2.26%
Praxis Precision Medicines Inc.
PRAX
US74006W2070
10231
2.01%
Alkermes PLC
ALKS
IE00B56GVS15
76233
1.93%
Crinetics Pharmaceuticals Inc.
CRNX
US22663K1079
46375
1.93%
ACADIA Pharmaceuticals Inc.
ACAD
US0042251084
78742
1.85%
Celcuity Inc.
CELC
US15102K1007
19584
1.85%
Viking Therapeutics Inc.
VKTX
US92686J1060
53659
1.78%
Akero Therapeutics Inc.
AKRO
US00973Y1082
36598
1.70%
Newamsterdam Pharma Co. NV
NAMS
NL00150012L7
54076
1.53%
Tarsus Pharmaceuticals Inc.
TARS
US87650L1035
21009
1.53%
Arcellx Inc.
ACLX
US03940C1009
24639
1.51%
Apogee Therapeutics Inc.
APGE
US03770N1019
21997
1.46%
Xenon Pharmaceuticals Inc.
XENE
CA98420N1050
36446
1.44%
Travere Therapeutics Inc.
TVTX
US89422G1076
46201
1.44%
Mirum Pharmaceuticals Inc.
MIRM
US6047491013
23531
1.42%
CG oncology Inc.
CGON
US1569441009
36738
1.37%
Disc Medicine Inc.
IRON
US2546041011
16423
1.32%
Ideaya Biosciences Inc.
IDYA
US45166A1025
41101
1.30%
Apellis Pharmaceuticals Inc.
APLS
US03753U1060
61489
1.28%
Amicus Therapeutics Inc.
FOLD
US03152W1099
144880
1.23%
Nuvation Bio Inc.
NUVB
US67080N1019
161127
1.22%
Denali Therapeutics Inc.
DNLI
US24823R1059
68576
1.20%
Vera Therapeutics Inc.
VERA
US92337R1014
30073
1.17%
Arcus Biosciences Inc.
RCUS
US03969F1093
51473
1.12%
Viridian Therapeutics Inc.
VRDN
US92790C1045
39035
1.09%
Terns Pharmaceuticals Inc.
TERN
US8808811074
41762
1.05%
Edgewise Therapeutics Inc.
EWTX
US28036F1057
50055
0.90%
Zai Lab Ltd.
ZLAB
US98887Q1040
51474
0.88%
Galapagos NV
GLPG
US36315X1019
31269
0.84%
Structure Therapeutics Inc.
GPCR
US86366E1064
27327
0.83%
Aurinia Pharmaceuticals Inc.
AUPH
CA05156V1022
59726
0.83%
Immunocore Holdings PLC
IMCR
US45258D1054
23844
0.82%
Celldex Therapeutics Inc.
CLDX
US15117B2025
31273
0.77%
Olema Pharmaceuticals Inc.
OLMA
US68062P1066
31823
0.76%
MannKind Corp.
MNKD
US56400P7069
149724
0.72%
Vericel Corp.
VCEL
US92346J1088
22324
0.71%
Pharvaris NV
PHVS
NL00150005Y4
30070
0.69%
Zenas Biopharma Inc.
ZBIO
US98937L1052
19576
0.69%
Trevi Therapeutics Inc.
TRVI
US89532M1018
57022
0.68%
Stoke Therapeutics Inc.
STOK
US86150R1077
24654
0.68%
Immunome Inc.
IMNM
US45257U1088
38398
0.67%
BioCryst Pharmaceuticals Inc.
BCRX
US09058V1035
98976
0.67%
Agios Pharmaceuticals Inc.
AGIO
US00847X1046
26968
0.63%
Upstream Bio Inc.
UPB
US91678A1079
25457
0.61%
Dianthus Therapeutics Inc.
DNTH
US2528281080
15334
0.55%
Relay Therapeutics Inc.
RLAY
US75943R1023
80449
0.52%
AnaptysBio Inc.
ANAB
US0327241065
13069
0.51%
Immatics NV
IMTX
NL0015285941
56625
0.51%
Xencor Inc.
XNCR
US98401F1057
33259
0.50%
Maze Therapeutics Inc.
MAZE
US5787841007
13452
0.50%
Capricor Therapeutics Inc.
CAPR
US14070B3096
20845
0.48%
Palvella Therapeutics Inc.
PVLA
US6979471090
5364
0.47%
MBX Biosciences Inc.
MBX
US55287L1017
16465
0.46%
Tyra Biosciences Inc.
TYRA
US90240B1061
24180
0.46%
Novavax Inc.
NVAX
US6700024010
73977
0.45%
UroGen Pharma Ltd.
URGN
IL0011407140
21857
0.44%
Rapport Therapeutics Inc.
RAPP
US75383L1026
16709
0.43%
ARS Pharmaceuticals Inc.
SPRY
US82835W1080
48215
0.42%
Bicara Therapeutics Inc.
BCAX
US0554771032
25849
0.41%
Kura Oncology Inc.
KURA
US50127T1097
38137
0.40%
MoonLake Immunotherapeutics
MLTX
KY61559X1045
30079
0.40%
Compass Therapeutics Inc.
CMPX
US20454B1044
81003
0.39%
Theravance Biopharma Inc.
TBPH
KYG8807B1068
23813
0.39%
Rezolute Inc.
RZLT
US76200L3096
41810
0.38%
Erasca Inc.
ERAS
US29479A1088
129037
0.38%
Vir Biotechnology Inc.
VIR
US92764N1028
64687
0.37%
Keros Therapeutics Inc.
KROS
US4923271013
19137
0.36%
Rigel Pharmaceuticals Inc.
RIGL
US7665597024
8198
0.35%
Fulgent Genetics Inc.
FLGT
US3596641098
14195
0.35%
Replimune Group Inc.
REPL
US76029N1063
36905
0.35%
Geron Corp.
GERN
US3741631036
295901
0.34%
Day One Biopharmaceuticals Inc.
DAWN
US23954D1090
47593
0.30%
Astria Therapeutics Inc.
ATXS
US04635X1028
25644
0.29%
Gossamer Bio Inc.
GOSS
US38341P1021
96308
0.28%
REGENXBIO Inc.
RGNX
US75901B1070
24198
0.25%
Prothena Corp. PLC
PRTA
IE00B91XRN20
25142
0.23%
Compass Pathways PLC
CMPS
US20451W1018
43912
0.19%
Annexon Inc.
ANNX
US03589W1027
46613
0.17%
Akebia Therapeutics Inc.
AKBA
US00972D1054
122968
0.17%
Autolus Therapeutics PLC
AUTL
US05280R1005
121388
0.15%
Bicycle Therapeutics PLC
BCYC
US0887861088
23627
0.15%
Anavex Life Sciences Corp.
AVXL
US0327973006
37779
0.14%
Delcath Systems Inc.
DCTH
US24661P8077
16493
0.13%
Vanda Pharmaceuticals Inc.
VNDA
US9216591084
26315
0.12%
Candel Therapeutics Inc.
CADL
US1374041093
25555
0.10%
Atea Pharmaceuticals Inc.
AVIR
US04683R1068
34616
0.08%
Arcturus Therapeutics Holdings Inc.
ARCT
US03969T1097
12534
0.06%
Tonix Pharmaceuticals Holding Corp.
TNXP
US8902608392
3453
0.00%
AstraZeneca PLC
2334482D
36586
0.00%
Radius Health CVR
RAD-CVR
28640
0.00%
Chinook Therapeutics Inc.
1835589D
20700
-0.02%
Cash and Equivalents
19784.34